Work Out to Exhaustion -- and Beyond -- With Carnosine

For years, elite athletes and their trainers have known that in order to increase muscle mass and strength, it’s necessary to work muscles to complete exhaustion, since it’s at the brink of muscle failure where the body’s ongoing protein synthesis is put on hold because available adenosine triphosphate (ATP) -- which is critical for protein synthesis -- is fully depleted by the contractions of the exercise. When the exercise ceases at the point of exhaustion, the body over-reacts, signaling muscle cell nuclei to drastically increase protein synthesis. It is thought that this results in super-increase of muscle protein.

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